TREM2-dependent lipid droplet biogenesis in phagocytes is required for remyelination

Upon demyelinating injury, microglia orchestrate a regenerative response that promotes myelin repair, thereby restoring rapid signal propagation and protecting axons from further damage. Whereas the essential phagocytic function of microglia for remyelination is well known, the underlying metabolic...

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Detalles Bibliográficos
Autores principales: Gouna, Garyfallia, Klose, Christian, Bosch-Queralt, Mar, Liu, Lu, Gokce, Ozgun, Schifferer, Martina, Cantuti-Castelvetri, Ludovico, Simons, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404472/
https://www.ncbi.nlm.nih.gov/pubmed/34424266
http://dx.doi.org/10.1084/jem.20210227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404472/
https://www.ncbi.nlm.nih.gov/pubmed/34424266
http://dx.doi.org/10.1084/jem.20210227

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