Characterization of human FDCs reveals regulation of T cells and antigen presentation to B cells

Stromal-derived follicular dendritic cells (FDCs) are essential for germinal centers (GCs), the site where B cells maturate their antibodies. FDCs present native antigen to B cells and maintain a CXCL13 gradient to form the B cell follicle. Yet despite their essential role, the transcriptome of huma...

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Detalles Bibliográficos
Autores principales: Heesters, Balthasar A., van Megesen, Kyah, Tomris, Ilhan, de Vries, Robert P., Magri, Giuliana, Spits, Hergen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Technical Advances and Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404474/
https://www.ncbi.nlm.nih.gov/pubmed/34424268
http://dx.doi.org/10.1084/jem.20210790

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404474/
https://www.ncbi.nlm.nih.gov/pubmed/34424268
http://dx.doi.org/10.1084/jem.20210790

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