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Loss of Tsc1 from striatal direct pathway neurons impairs endocannabinoid-LTD and enhances motor routine learning

Tuberous sclerosis complex (TSC) is a neurodevelopmental disorder that often presents with psychiatric conditions, including autism spectrum disorder (ASD). ASD is characterized by restricted, repetitive, and inflexible behaviors, which may result from abnormal activity in striatal circuits that med...

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Detalles Bibliográficos
Autores principales: Benthall, Katelyn N., Cording, Katherine R., Agopyan-Miu, Alexander H.C.W., Wong, Corinna D., Chen, Emily Y., Bateup, Helen S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404511/
https://www.ncbi.nlm.nih.gov/pubmed/34380034
http://dx.doi.org/10.1016/j.celrep.2021.109511