Profiling Transcription Initiation in Peripheral Leukocytes Reveals Severity-Associated Cis-Regulatory Elements in Critical COVID-19

The contribution of transcription factors (TFs) and gene regulatory programs in the immune response to COVID-19 and their relationship to disease outcome is not fully understood. Analysis of genome-wide changes in transcription at both promoter-proximal and distal cis-regulatory DNA elements, collec...

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Detalles Bibliográficos
Autores principales: Lam, Michael Tun Yin, Duttke, Sascha H., Odish, Mazen F., Le, Hiep D., Hansen, Emily A., Nguyen, Celina T., Trescott, Samantha, Kim, Roy, Deota, Shaunak, Chang, Max W., Patel, Arjun, Hepokoski, Mark, Alotaibi, Mona, Rolfsen, Mark, Perofsky, Katherine, Warden, Anna S., Foley, Jennifer, Ramirez, Sydney I, Dan, Jennifer M., Abbott, Robert K, Crotty, Shane, Crotty Alexander, Laura E, Malhotra, Atul, Panda, Satchidananda, Benner, Christopher W., Coufal, Nicole G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404884/
https://www.ncbi.nlm.nih.gov/pubmed/34462742
http://dx.doi.org/10.1101/2021.08.24.457187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404884/
https://www.ncbi.nlm.nih.gov/pubmed/34462742
http://dx.doi.org/10.1101/2021.08.24.457187

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