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Profiling Transcription Initiation in Peripheral Leukocytes Reveals Severity-Associated Cis-Regulatory Elements in Critical COVID-19
The contribution of transcription factors (TFs) and gene regulatory programs in the immune response to COVID-19 and their relationship to disease outcome is not fully understood. Analysis of genome-wide changes in transcription at both promoter-proximal and distal cis-regulatory DNA elements, collec...
Autores principales: | Lam, Michael Tun Yin, Duttke, Sascha H., Odish, Mazen F., Le, Hiep D., Hansen, Emily A., Nguyen, Celina T., Trescott, Samantha, Kim, Roy, Deota, Shaunak, Chang, Max W., Patel, Arjun, Hepokoski, Mark, Alotaibi, Mona, Rolfsen, Mark, Perofsky, Katherine, Warden, Anna S., Foley, Jennifer, Ramirez, Sydney I, Dan, Jennifer M., Abbott, Robert K, Crotty, Shane, Crotty Alexander, Laura E, Malhotra, Atul, Panda, Satchidananda, Benner, Christopher W., Coufal, Nicole G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404884/ https://www.ncbi.nlm.nih.gov/pubmed/34462742 http://dx.doi.org/10.1101/2021.08.24.457187 |
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