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Effects of Spike Mutations in SARS-CoV-2 Variants of Concern on Human or Animal ACE2-Mediated Virus Entry and Neutralization

SARS-CoV-2 is a zoonotic agent capable of infecting humans and a wide range of animal species. Over the duration of the pandemic, mutations in the SARS-CoV-2 Spike protein (S) have arisen in circulating viral populations, culminating in the spread of several variants of concern (VOC) with varying de...

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Detalles Bibliográficos
Autores principales: Kim, Yunjeong, Gaudreault, Natasha N, Meekins, David A., Perera, Krishani D, Bold, Dashzeveg, Trujillo, Jessie D., Morozov, Igor, McDowell, Chester D., Chang, Kyeong-Ok, Richt, Juergen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404895/
https://www.ncbi.nlm.nih.gov/pubmed/34462749
http://dx.doi.org/10.1101/2021.08.25.457627