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EBV latent membrane proteins promote hybrid epithelial-mesenchymal and extreme mesenchymal states of nasopharyngeal carcinoma cells for tumorigenicity

EBV-encoded LMPs are consistently detected in nasopharyngeal carcinoma (NPC). Recent evidence suggests potential roles of LMP1 and LMP2A in Epithelial-to-mesenchymal transition (EMT) process in NPC. EMT engages in the generation and maintenance of cancer stem cells (CSCs) and confers on cancer cells...

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Detalles Bibliográficos
Autores principales: Zhu, Nannan, Xu, Xiaoting, Wang, Yan, Zeng, Mu-Sheng, Yuan, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405006/
https://www.ncbi.nlm.nih.gov/pubmed/34407150
http://dx.doi.org/10.1371/journal.ppat.1009873