Teaching old mice new tricks: the utility of aged mouse models of C. difficile infection to study pathogenesis and rejuvenate immune response

BACKGROUND: Clostridioides difficile is a serious problem for the aging population. Aged mouse model of C. difficile infection (CDI) has emerged as a valuable tool to evaluate the mechanism of aging in CDI. METHODS: We reviewed five published studies utilizing aged mice (7–28 months) for CDI model f...

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Detalles Bibliográficos
Autores principales: Shin, Jae Hyun, Pawlowski, Sean W., Warren, Cirle A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Commentary and Views
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405153/
https://www.ncbi.nlm.nih.gov/pubmed/34432545
http://dx.doi.org/10.1080/19490976.2021.1966255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405153/
https://www.ncbi.nlm.nih.gov/pubmed/34432545
http://dx.doi.org/10.1080/19490976.2021.1966255

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