Protective Effect of Penetratin Analogue-Tagged SOD1 on Cisplatin-Induced Nephrotoxicity through Inhibiting Oxidative Stress and JNK/p38 MAPK Signaling Pathway

Copper/zinc superoxide dismutase (SOD1) can clear cisplatin- (CP-) induced excessive reactive oxygen species (ROS), but exogenous SOD1 cannot enter cells because of its low biomembrane permeability. Cell-penetrating peptides (CPPs) can rapidly cross plasma membranes. This study is aimed at identifyi...

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Detalles Bibliográficos
Autores principales: Wang, Xiao-lu, Wang, Liang, Lin, Fo-lan, Li, Si-si, Lin, Ting-xuan, Jiang, Ren-wang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405295/
https://www.ncbi.nlm.nih.gov/pubmed/34471466
http://dx.doi.org/10.1155/2021/5526053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405295/
https://www.ncbi.nlm.nih.gov/pubmed/34471466
http://dx.doi.org/10.1155/2021/5526053

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