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Protective Effect of Penetratin Analogue-Tagged SOD1 on Cisplatin-Induced Nephrotoxicity through Inhibiting Oxidative Stress and JNK/p38 MAPK Signaling Pathway
Copper/zinc superoxide dismutase (SOD1) can clear cisplatin- (CP-) induced excessive reactive oxygen species (ROS), but exogenous SOD1 cannot enter cells because of its low biomembrane permeability. Cell-penetrating peptides (CPPs) can rapidly cross plasma membranes. This study is aimed at identifyi...
Autores principales: | Wang, Xiao-lu, Wang, Liang, Lin, Fo-lan, Li, Si-si, Lin, Ting-xuan, Jiang, Ren-wang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405295/ https://www.ncbi.nlm.nih.gov/pubmed/34471466 http://dx.doi.org/10.1155/2021/5526053 |
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