TRPV1 Channel Activated by the PGE2/EP4 Pathway Mediates Spinal Hypersensitivity in a Mouse Model of Vertebral Endplate Degeneration

Low back pain (LBP) is the primary cause of disability globally. There is a close relationship between Modic changes or endplate defects and LBP. Endplates undergo ossification and become highly porous during intervertebral disc (IVD) degeneration. In our study, we used a mouse model of vertebral en...

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Detalles Bibliográficos
Autores principales: Liu, Sijing, Wang, Qiong, Li, Ziyi, Ma, Lei, Li, Ting, Li, Yukun, Wang, Na, Liu, Chang, Xue, Peng, Wang, Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405310/
https://www.ncbi.nlm.nih.gov/pubmed/34471470
http://dx.doi.org/10.1155/2021/9965737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405310/
https://www.ncbi.nlm.nih.gov/pubmed/34471470
http://dx.doi.org/10.1155/2021/9965737

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