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Loss of RAR-α and RXR-α and enhanced caspase-3-dependent apoptosis in N-acetyl-p-aminophenol-induced liver injury in mice is tissue factor dependent

Tissue factor (TF) activates the coagulation system and has an important role in the pathogenesis of various diseases. Our previous study stated that retinoid receptors (RAR-α and RXR-α) are released as a lipid droplet in monocrotaline/lipopolysaccharide-induced idiosyncratic liver toxicity in mice....

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Detalles Bibliográficos
Autores principales: Abdel-Bakky, Mohamed Sadek, Helal, Gouda Kamel, El-Sayed, El-Sayed Mohamed, Amin, Elham, Alqasoumi, Abdulmajeed, Alhowail, Ahmad, Abdelmoti, Eman Sayed Said, Saad, Ahmed Saad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405435/
https://www.ncbi.nlm.nih.gov/pubmed/34448456
http://dx.doi.org/10.4196/kjpp.2021.25.5.385