Simultaneous quantification of trimethylamine N-oxide, trimethylamine, choline, betaine, creatinine, and propionyl-, acetyl-, and l-carnitine in clinical and food samples using HILIC-LC-MS

Trimethylamine-N-oxide (TMAO), a microbiome-derived metabolite from the metabolism of choline, betaine, and carnitines, is associated to adverse cardiovascular outcomes. A method suitable for routine quantification of TMAO and its precursors (trimethylamine (TMA), choline, betaine, creatinine, and p...

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Detalles Bibliográficos
Autores principales: Hefni, Mohammed E, Bergström, Maria, Lennqvist, Torbjörn, Fagerström, Cecilia, Witthöft, Cornelia M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405501/
https://www.ncbi.nlm.nih.gov/pubmed/34258650
http://dx.doi.org/10.1007/s00216-021-03509-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405501/
https://www.ncbi.nlm.nih.gov/pubmed/34258650
http://dx.doi.org/10.1007/s00216-021-03509-y

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