Protocatechuic acid attenuates isoproterenol-induced cardiac hypertrophy via downregulation of ROCK1–Sp1–PKCγ axis

Cardiac hypertrophy is an adaptive response of the myocardium to pressure overload or adrenergic agonists. Here, we investigated the protective effects and the regulatory mechanism of protocatechuic acid, a phenolic compound, using a mouse model of isoproterenol-induced cardiac hypertrophy. Our resu...

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Detalles Bibliográficos
Autores principales: Bai, Liyan, Kee, Hae Jin, Han, Xiongyi, Zhao, Tingwei, Kee, Seung-Jung, Jeong, Myung Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405624/
https://www.ncbi.nlm.nih.gov/pubmed/34462460
http://dx.doi.org/10.1038/s41598-021-96761-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405624/
https://www.ncbi.nlm.nih.gov/pubmed/34462460
http://dx.doi.org/10.1038/s41598-021-96761-2

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