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Ribosomal proteins and human diseases: molecular mechanisms and targeted therapy

Ribosome biogenesis and protein synthesis are fundamental rate-limiting steps for cell growth and proliferation. The ribosomal proteins (RPs), comprising the structural parts of the ribosome, are essential for ribosome assembly and function. In addition to their canonical ribosomal functions, multip...

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Detalles Bibliográficos
Autores principales: Kang, Jian, Brajanovski, Natalie, Chan, Keefe T., Xuan, Jiachen, Pearson, Richard B., Sanij, Elaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405630/
https://www.ncbi.nlm.nih.gov/pubmed/34462428
http://dx.doi.org/10.1038/s41392-021-00728-8