Transcriptional overlap links DNA hypomethylation with DNA hypermethylation at adjacent promoters in cancer

Tumor development involves alterations in DNA methylation patterns, which include both gains (hypermethylation) and losses (hypomethylation) in different genomic regions. The mechanisms underlying these two opposite, yet co-existing, alterations in tumors remain unclear. While studying the human MAG...

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Detalles Bibliográficos
Autores principales: Fain, Jean S., Loriot, Axelle, Diacofotaki, Anna, Van Tongelen, Aurélie, De Smet, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405634/
https://www.ncbi.nlm.nih.gov/pubmed/34462486
http://dx.doi.org/10.1038/s41598-021-96844-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405634/
https://www.ncbi.nlm.nih.gov/pubmed/34462486
http://dx.doi.org/10.1038/s41598-021-96844-0

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