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Transcriptional overlap links DNA hypomethylation with DNA hypermethylation at adjacent promoters in cancer
Tumor development involves alterations in DNA methylation patterns, which include both gains (hypermethylation) and losses (hypomethylation) in different genomic regions. The mechanisms underlying these two opposite, yet co-existing, alterations in tumors remain unclear. While studying the human MAG...
Autores principales: | Fain, Jean S., Loriot, Axelle, Diacofotaki, Anna, Van Tongelen, Aurélie, De Smet, Charles |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405634/ https://www.ncbi.nlm.nih.gov/pubmed/34462486 http://dx.doi.org/10.1038/s41598-021-96844-0 |
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