2-Carba-lysophosphatidic acid is a novel β-lysophosphatidic acid analogue with high potential for lysophosphatidic acid receptor activation and autotaxin inhibition

Cyclic phosphatidic acid (cPA) is a naturally occurring phospholipid mediator that, along with its chemically stabilized analogue 2-carba-cyclic phosphatidic acid (2ccPA), induces various biological activities in vitro and in vivo. Although cPA is similar to lysophosphatidic acid (LPA) in structure...

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Detalles Bibliográficos
Autores principales: Fukasawa, Keiko, Gotoh, Mari, Uwamizu, Akiharu, Hirokawa, Takatsugu, Ishikawa, Masaki, Shimizu, Yoshibumi, Yamamoto, Shinji, Iwasa, Kensuke, Yoshikawa, Keisuke, Aoki, Junken, Murakami-Murofushi, Kimiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405639/
https://www.ncbi.nlm.nih.gov/pubmed/34462512
http://dx.doi.org/10.1038/s41598-021-96931-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405639/
https://www.ncbi.nlm.nih.gov/pubmed/34462512
http://dx.doi.org/10.1038/s41598-021-96931-2

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