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S100P contributes to promoter demethylation and transcriptional activation of SLC2A5 to promote metastasis in colorectal cancer

BACKGROUND: SLC2A5 is a high-affinity fructose transporter, which is frequently upregulated in multiple human malignant tumours. However, the function and molecular mechanism of SLC2A5 in colorectal cancer (CRC) remain unknown. METHODS: We detected the expression levels of SLC2A5 in CRC tissues and...

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Detalles Bibliográficos
Autores principales: Lin, Mingdao, Fang, Yuan, Li, Zhenkang, Li, Yongsheng, Feng, Xiaochuang, Zhan, Yizhi, Xie, Yuwen, Liu, Yuechen, Liu, Zehao, Li, Guoxin, Shen, Zhiyong, Deng, Haijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405647/
https://www.ncbi.nlm.nih.gov/pubmed/34188196
http://dx.doi.org/10.1038/s41416-021-01306-z