The Smac mimetic BV6 cooperates with STING to induce necroptosis in apoptosis-resistant pancreatic carcinoma cells

Pancreatic cancer (PC) still remains a major cause of cancer-related death worldwide and alternative treatments are urgently required. A common problem of PC is the development of resistance against apoptosis that limits therapeutic success. Here we demonstrate that the prototypical Smac mimetic BV6...

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Detalles Bibliográficos
Autores principales: Hannes, Sabine, Karlowitz, Rebekka, van Wijk, Sjoerd J. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405653/
https://www.ncbi.nlm.nih.gov/pubmed/34462421
http://dx.doi.org/10.1038/s41419-021-04014-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405653/
https://www.ncbi.nlm.nih.gov/pubmed/34462421
http://dx.doi.org/10.1038/s41419-021-04014-x

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