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The Smac mimetic BV6 cooperates with STING to induce necroptosis in apoptosis-resistant pancreatic carcinoma cells

Pancreatic cancer (PC) still remains a major cause of cancer-related death worldwide and alternative treatments are urgently required. A common problem of PC is the development of resistance against apoptosis that limits therapeutic success. Here we demonstrate that the prototypical Smac mimetic BV6...

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Detalles Bibliográficos
Autores principales:	Hannes, Sabine, Karlowitz, Rebekka, van Wijk, Sjoerd J. L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405653/ https://www.ncbi.nlm.nih.gov/pubmed/34462421 http://dx.doi.org/10.1038/s41419-021-04014-x

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