Myocarditis occurrence with cancer immunotherapy across indications in clinical trial and post-marketing data

Antibodies targeting the PD-1, PD-L1, and CTLA-4 immune checkpoint axis have been used in a variety of tumor types. They achieve anti-tumor activity through activating the patient’s own immune system to target immune response evading cancer cells. However, this unique mechanism of action may cause i...

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Detalles Bibliográficos
Autores principales: Makunts, Tigran, Saunders, Ila M., Cohen, Isaac V., Li, Mengxing, Moumedjian, Talar, Issa, Masara A., Burkhart, Keith, Lee, Peter, Patel, Sandip Pravin, Abagyan, Ruben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405813/
https://www.ncbi.nlm.nih.gov/pubmed/34462476
http://dx.doi.org/10.1038/s41598-021-96467-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405813/
https://www.ncbi.nlm.nih.gov/pubmed/34462476
http://dx.doi.org/10.1038/s41598-021-96467-5

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