AEG-1 silencing attenuates M2-polarization of glioma-associated microglia/macrophages and sensitizes glioma cells to temozolomide

Glioma is the most frequent primary malignancy in the brain; temozolomide (TMZ) is the first-line chemotherapeutic agent used to combat this tumor. We showed here that astrocyte elevated gene-1 (AEG-1) was overexpressed in glioma tissues and associated with a worse subtype and a poor prognosis. CCK-...

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Detalles Bibliográficos
Autores principales: Li, Jing, Sun, Yuchen, Sun, Xuanzi, Zhao, Xu, Ma, Yuan, Wang, Yuzhu, Zhang, Xiaozhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405821/
https://www.ncbi.nlm.nih.gov/pubmed/34462446
http://dx.doi.org/10.1038/s41598-021-96647-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405821/
https://www.ncbi.nlm.nih.gov/pubmed/34462446
http://dx.doi.org/10.1038/s41598-021-96647-3

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