Identification of candidate miRNA biomarkers for facioscapulohumeral muscular dystrophy using DUX4-based mouse models

Facioscapulohumeral muscular dystrophy (FSHD) is caused by misexpression of DUX4 in skeletal myocytes. As DUX4 is the key therapeutic target in FSHD, surrogate biomarkers of DUX4 expression in skeletal muscle are critically needed for clinical trials. Although no natural animal models of FSHD exist,...

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Detalles Bibliográficos
Autores principales: Nunes, Andreia M., Ramirez, Monique, Jones, Takako I., Jones, Peter L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405850/
https://www.ncbi.nlm.nih.gov/pubmed/34338285
http://dx.doi.org/10.1242/dmm.049016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405850/
https://www.ncbi.nlm.nih.gov/pubmed/34338285
http://dx.doi.org/10.1242/dmm.049016

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