Activation of innate immunity during development induces unresolved dysbiotic inflammatory gut and shortens lifespan

An early-life inflammatory response is associated with risks of age-related pathologies. How transient immune signalling activity during animal development influences life-long fitness is not well understood. Using Drosophila as a model, we find that activation of innate immune pathway Immune defici...

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Detalles Bibliográficos
Autores principales: Yamashita, Kyoko, Oi, Ayano, Kosakamoto, Hina, Yamauchi, Toshitaka, Kadoguchi, Hibiki, Kuraishi, Takayuki, Miura, Masayuki, Obata, Fumiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405880/
https://www.ncbi.nlm.nih.gov/pubmed/34448472
http://dx.doi.org/10.1242/dmm.049103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405880/
https://www.ncbi.nlm.nih.gov/pubmed/34448472
http://dx.doi.org/10.1242/dmm.049103

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