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Activation of innate immunity during development induces unresolved dysbiotic inflammatory gut and shortens lifespan
An early-life inflammatory response is associated with risks of age-related pathologies. How transient immune signalling activity during animal development influences life-long fitness is not well understood. Using Drosophila as a model, we find that activation of innate immune pathway Immune defici...
Autores principales: | Yamashita, Kyoko, Oi, Ayano, Kosakamoto, Hina, Yamauchi, Toshitaka, Kadoguchi, Hibiki, Kuraishi, Takayuki, Miura, Masayuki, Obata, Fumiaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405880/ https://www.ncbi.nlm.nih.gov/pubmed/34448472 http://dx.doi.org/10.1242/dmm.049103 |
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