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CD147 mediates the CD44s-dependent differentiation of myofibroblasts driven by transforming growth factor-β(1)
Progressive fibrosis leads to loss of organ function and affects many organs as a result of excessive extracellular matrix production. The ubiquitous matrix polysaccharide hyaluronan (HA) is central to this through association with its primary receptor, CD44, which exists as standard CD44 (CD44s) or...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405944/ https://www.ncbi.nlm.nih.gov/pubmed/34364871 http://dx.doi.org/10.1016/j.jbc.2021.100987 |