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CD147 mediates the CD44s-dependent differentiation of myofibroblasts driven by transforming growth factor-β(1)
Progressive fibrosis leads to loss of organ function and affects many organs as a result of excessive extracellular matrix production. The ubiquitous matrix polysaccharide hyaluronan (HA) is central to this through association with its primary receptor, CD44, which exists as standard CD44 (CD44s) or...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405944/ https://www.ncbi.nlm.nih.gov/pubmed/34364871 http://dx.doi.org/10.1016/j.jbc.2021.100987 |