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Minimal protein-only RNase P structure reveals insights into tRNA precursor recognition and catalysis

Ribonuclease P (RNase P) is an endoribonuclease that catalyzes the processing of the 5′ leader sequence of precursor tRNA (pre-tRNA). Ribonucleoprotein RNase P and protein-only RNase P (PRORP) in eukaryotes have been extensively studied, but the mechanism by which a prokaryotic nuclease recognizes a...

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Detalles Bibliográficos
Autores principales: Teramoto, Takamasa, Koyasu, Takeshi, Adachi, Naruhiko, Kawasaki, Masato, Moriya, Toshio, Numata, Tomoyuki, Senda, Toshiya, Kakuta, Yoshimitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8405995/
https://www.ncbi.nlm.nih.gov/pubmed/34339732
http://dx.doi.org/10.1016/j.jbc.2021.101028