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Vitamin K supplementation and arterial calcification in dialysis: results of the double-blind, randomized, placebo-controlled RenaKvit trial

BACKGROUND: Arterial calcification is associated with cardiovascular mortality in dialysis patients. Active matrix Gla protein (MGP) is a vitamin K-dependent inhibitor of arterial calcification. Elevated plasma concentrations of inactive MGP, i.e. dephosphorylated-uncarboxylated MGP (dp-ucMGP), are...

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Detalles Bibliográficos
Autores principales: Levy-Schousboe, Karin, Frimodt-Møller, Marie, Hansen, Ditte, Peters, Christian Daugaard, Kjærgaard, Krista Dybtved, Jensen, Jens Dam, Strandhave, Charlotte, Elming, Hanne, Larsen, Carsten Toftager, Sandstrøm, Hanne, Brasen, Claus Lohman, Schmedes, Anne, Madsen, Jonna Skov, Jørgensen, Niklas Rye, Frøkjær, Jens Brøndum, Frandsen, Niels Erik, Petersen, Inge, Marckmann, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406073/
https://www.ncbi.nlm.nih.gov/pubmed/34476095
http://dx.doi.org/10.1093/ckj/sfab017