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Signaling through Syk or CARD9 Mediates Species-Specific Anti-Candida Protection in Bone Marrow Chimeric Mice

The spleen tyrosine kinase (Syk) and the downstream adaptor protein CARD9 are crucial signaling molecules in antimicrobial immunity. Candida parapsilosis is an emerging fungal pathogen with a high incidence in neonates, while Candida albicans is the most common agent of candidiasis. While signaling...

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Detalles Bibliográficos
Autores principales: Zajta, Erik, Csonka, Katalin, Tóth, Adél, Tiszlavicz, Laszló, Németh, Tamás, Orosz, Anita, Novák, Ádám, Csikós, Máté, Vágvölgyi, Csaba, Mócsai, Attila, Gácser, Attila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406149/
https://www.ncbi.nlm.nih.gov/pubmed/34465030
http://dx.doi.org/10.1128/mBio.01608-21