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Dynamics of SARS-CoV-2 Spike Proteins in Cell Entry: Control Elements in the Amino-Terminal Domains

Selective pressures drive adaptive changes in the coronavirus spike proteins directing virus-cell entry. These changes are concentrated in the amino-terminal domains (NTDs) and the receptor-binding domains (RBDs) of complex modular spike protein trimers. The impact of this hypervariability on virus...

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Detalles Bibliográficos
Autores principales: Qing, Enya, Kicmal, Tom, Kumar, Binod, Hawkins, Grant M., Timm, Emily, Perlman, Stanley, Gallagher, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406164/
https://www.ncbi.nlm.nih.gov/pubmed/34340537
http://dx.doi.org/10.1128/mBio.01590-21