Murine Monoclonal Antibodies against the Receptor Binding Domain of SARS-CoV-2 Neutralize Authentic Wild-Type SARS-CoV-2 as Well as B.1.1.7 and B.1.351 Viruses and Protect In Vivo in a Mouse Model in a Neutralization-Dependent Manner

After first emerging in late 2019 in China, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has since caused a pandemic leading to millions of infections and deaths worldwide. Vaccines have been developed and authorized, but the supply of these vaccines is currently limited. With new va...

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Detalles Bibliográficos
Autores principales: Amanat, Fatima, Strohmeier, Shirin, Lee, Wen-Hsin, Bangaru, Sandhya, Ward, Andrew B., Coughlan, Lynda, Krammer, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406178/
https://www.ncbi.nlm.nih.gov/pubmed/34311574
http://dx.doi.org/10.1128/mBio.01002-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406178/
https://www.ncbi.nlm.nih.gov/pubmed/34311574
http://dx.doi.org/10.1128/mBio.01002-21

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