Murine Monoclonal Antibodies against the Receptor Binding Domain of SARS-CoV-2 Neutralize Authentic Wild-Type SARS-CoV-2 as Well as B.1.1.7 and B.1.351 Viruses and Protect In Vivo in a Mouse Model in a Neutralization-Dependent Manner

After first emerging in late 2019 in China, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has since caused a pandemic leading to millions of infections and deaths worldwide. Vaccines have been developed and authorized, but the supply of these vaccines is currently limited. With new va...

Descripción completa

Detalles Bibliográficos
Autores principales: Amanat, Fatima, Strohmeier, Shirin, Lee, Wen-Hsin, Bangaru, Sandhya, Ward, Andrew B., Coughlan, Lynda, Krammer, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406178/
https://www.ncbi.nlm.nih.gov/pubmed/34311574
http://dx.doi.org/10.1128/mBio.01002-21

Ejemplares similares

Ejemplares similares