SAMase of Bacteriophage T3 Inactivates Escherichia coli’s Methionine S-Adenosyltransferase by Forming Heteropolymers

S-Adenosylmethionine lyase (SAMase) of bacteriophage T3 degrades the intracellular SAM pools of the host Escherichia coli cells, thereby inactivating a crucial metabolite involved in a plethora of cellular functions, including DNA methylation. SAMase is the first viral protein expressed upon infecti...

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Detalles Bibliográficos
Autores principales: Simon-Baram, Hadas, Kleiner, Daniel, Shmulevich, Fannia, Zarivach, Raz, Zalk, Ran, Tang, Huayuan, Ding, Feng, Bershtein, Shimon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Observation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406200/
https://www.ncbi.nlm.nih.gov/pubmed/34340545
http://dx.doi.org/10.1128/mBio.01242-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406200/
https://www.ncbi.nlm.nih.gov/pubmed/34340545
http://dx.doi.org/10.1128/mBio.01242-21

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