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Evolution towards Virulence in a Burkholderia Two-Component System

Bacteria in the Burkholderia cepacia complex (BCC) are significant pathogens for people with cystic fibrosis (CF) and are often extensively antibiotic resistant. Here, we assess the impacts of clinically observed mutations in fixL, which encodes the sensor histidine kinase FixL. FixL along with FixJ...

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Detalles Bibliográficos
Autores principales: Schaefers, Matthew M., Wang, Benjamin X., Boisvert, Nicole M., Martini, Sarah J., Bonney, Sarah L., Marshall, Christopher W., Laub, Michael T., Cooper, Vaughn S., Priebe, Gregory P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406202/
https://www.ncbi.nlm.nih.gov/pubmed/34372701
http://dx.doi.org/10.1128/mBio.01823-21