Turnover of Variant Surface Glycoprotein in Trypanosoma brucei Is a Bimodal Process

African trypanosomes utilize glycosylphosphatidylinositol (GPI)-anchored variant surface glycoprotein (VSG) to evade the host immune system. VSG turnover is thought to be mediated via cleavage of the GPI anchor by endogenous GPI-specific phospholipase C (GPI-PLC). However, GPI-PLC is topologically s...

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Detalles Bibliográficos
Autores principales: Garrison, Paige, Khan, Umaer, Cipriano, Michael, Bush, Peter J., McDonald, Jacquelyn, Sur, Aakash, Myler, Peter J., Smith, Terry K., Hajduk, Stephen L., Bangs, James D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406259/
https://www.ncbi.nlm.nih.gov/pubmed/34311578
http://dx.doi.org/10.1128/mBio.01725-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406259/
https://www.ncbi.nlm.nih.gov/pubmed/34311578
http://dx.doi.org/10.1128/mBio.01725-21

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