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Multifactorial Role of Mitochondria in Echinocandin Tolerance Revealed by Transcriptome Analysis of Drug-Tolerant Cells

Fungal infections cause significant mortality and morbidity worldwide, and the limited existing antifungal reservoir is further weakened by the emergence of strains resistant to echinocandins, a first line of antifungal therapy. Candida glabrata is an opportunistic fungal pathogen that rapidly devel...

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Detalles Bibliográficos
Autores principales: Garcia-Rubio, Rocio, Jimenez-Ortigosa, Cristina, DeGregorio, Lucius, Quinteros, Christopher, Shor, Erika, Perlin, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406274/
https://www.ncbi.nlm.nih.gov/pubmed/34372698
http://dx.doi.org/10.1128/mBio.01959-21