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Orientia tsutsugamushi Nucleomodulin Ank13 Exploits the RaDAR Nuclear Import Pathway To Modulate Host Cell Transcription

Orientia tsutsugamushi is the etiologic agent of scrub typhus, the deadliest of all diseases caused by obligate intracellular bacteria. Nucleomodulins, bacterial effectors that dysregulate eukaryotic transcription, are being increasingly recognized as key virulence factors. How they translocate into...

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Detalles Bibliográficos
Autores principales: Adcox, Haley E., Hatke, Amanda L., Andersen, Shelby E., Gupta, Sarika, Otto, Nathan B., Weber, Mary M., Marconi, Richard T., Carlyon, Jason A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406279/
https://www.ncbi.nlm.nih.gov/pubmed/34340535
http://dx.doi.org/10.1128/mBio.01816-21