Highly Basic Clusters in the Herpes Simplex Virus 1 Nuclear Egress Complex Drive Membrane Budding by Inducing Lipid Ordering

During replication of herpesviruses, capsids escape from the nucleus into the cytoplasm by budding at the inner nuclear membrane. This unusual process is mediated by the viral nuclear egress complex (NEC) that deforms the membrane around the capsid by oligomerizing into a hexagonal, membrane-bound s...

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Detalles Bibliográficos
Autores principales: Thorsen, Michael K., Lai, Alex, Lee, Michelle W., Hoogerheide, David P., Wong, Gerard C. L., Freed, Jack H., Heldwein, Ekaterina E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406295/
https://www.ncbi.nlm.nih.gov/pubmed/34425706
http://dx.doi.org/10.1128/mBio.01548-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406295/
https://www.ncbi.nlm.nih.gov/pubmed/34425706
http://dx.doi.org/10.1128/mBio.01548-21

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