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Highly Basic Clusters in the Herpes Simplex Virus 1 Nuclear Egress Complex Drive Membrane Budding by Inducing Lipid Ordering
During replication of herpesviruses, capsids escape from the nucleus into the cytoplasm by budding at the inner nuclear membrane. This unusual process is mediated by the viral nuclear egress complex (NEC) that deforms the membrane around the capsid by oligomerizing into a hexagonal, membrane-bound s...
Autores principales: | Thorsen, Michael K., Lai, Alex, Lee, Michelle W., Hoogerheide, David P., Wong, Gerard C. L., Freed, Jack H., Heldwein, Ekaterina E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406295/ https://www.ncbi.nlm.nih.gov/pubmed/34425706 http://dx.doi.org/10.1128/mBio.01548-21 |
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