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Discovery of Fungus-Specific Targets and Inhibitors Using Chemical Phenotyping of Pathogenic Spore Germination

There is a critical need for new antifungal drugs; however, the lack of available fungus-specific targets is a major hurdle in the development of antifungal therapeutics. Spore germination is a differentiation process absent in humans that could harbor uncharacterized fungus-specific targets. To cap...

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Detalles Bibliográficos
Autores principales: Ortiz, Sébastien C., Huang, Mingwei, Hull, Christina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406298/
https://www.ncbi.nlm.nih.gov/pubmed/34311572
http://dx.doi.org/10.1128/mBio.01672-21