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Discovery of Fungus-Specific Targets and Inhibitors Using Chemical Phenotyping of Pathogenic Spore Germination
There is a critical need for new antifungal drugs; however, the lack of available fungus-specific targets is a major hurdle in the development of antifungal therapeutics. Spore germination is a differentiation process absent in humans that could harbor uncharacterized fungus-specific targets. To cap...
Autores principales: | Ortiz, Sébastien C., Huang, Mingwei, Hull, Christina M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406298/ https://www.ncbi.nlm.nih.gov/pubmed/34311572 http://dx.doi.org/10.1128/mBio.01672-21 |
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