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Inhibiting Type VI Secretion System Activity with a Biomimetic Peptide Designed To Target the Baseplate Wedge Complex

Human health is threatened by bacterial infections that are increasingly resistant to multiple drugs. A recently emerged strategy consists of disarming pathogenic bacteria by targeting and blocking their virulence factors. The type VI secretion system (T6SS) is a widespread secretion nanomachine enc...

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Detalles Bibliográficos
Autores principales: Cherrak, Y., Filella-Merce, I., Schmidt, V., Byrne, D., Sgoluppi, V., Chaiaheloudjou, R., Betzi, S., Morelli, X., Nilges, M., Pellarin, R., Durand, E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406304/
https://www.ncbi.nlm.nih.gov/pubmed/34372705
http://dx.doi.org/10.1128/mBio.01348-21