Change in Cofactor Specificity of Oxidoreductases by Adaptive Evolution of an Escherichia coli NADPH-Auxotrophic Strain

The nicotinamide cofactor specificity of enzymes plays a key role in regulating metabolic processes and attaining cellular homeostasis. Multiple studies have used enzyme engineering tools or a directed evolution approach to switch the cofactor preference of specific oxidoreductases. However, whole-c...

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Detalles Bibliográficos
Autores principales: Bouzon, Madeleine, Döring, Volker, Dubois, Ivan, Berger, Anne, Stoffel, Gabriele M. M., Calzadiaz Ramirez, Liliana, Meyer, Sophia N., Fouré, Marion, Roche, David, Perret, Alain, Erb, Tobias J., Bar-Even, Arren, Lindner, Steffen N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406311/
https://www.ncbi.nlm.nih.gov/pubmed/34399608
http://dx.doi.org/10.1128/mBio.00329-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406311/
https://www.ncbi.nlm.nih.gov/pubmed/34399608
http://dx.doi.org/10.1128/mBio.00329-21

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