Galectin-8 Senses Phagosomal Damage and Recruits Selective Autophagy Adapter TAX1BP1 To Control Mycobacterium tuberculosis Infection in Macrophages

Mycobacterium tuberculosis (Mtb) causes one of the deadliest infectious diseases worldwide. Upon infection, Mtb is phagocytosed by macrophages and uses its virulence-associated ESX-1 secretion system to modulate the host cell. We showed previously that the ESX-1 secretion system perturbs the Mtb-con...

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Detalles Bibliográficos
Autores principales: Bell, Samantha L., Lopez, Kayla L., Cox, Jeffery S., Patrick, Kristin L., Watson, Robert O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406326/
https://www.ncbi.nlm.nih.gov/pubmed/34225486
http://dx.doi.org/10.1128/mBio.01871-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406326/
https://www.ncbi.nlm.nih.gov/pubmed/34225486
http://dx.doi.org/10.1128/mBio.01871-20

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