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CCR2 Signaling Promotes Brain Infiltration of Inflammatory Monocytes and Contributes to Neuropathology during Cryptococcal Meningoencephalitis

Cryptococcal meningoencephalitis (CM) is a leading cause of central nervous system (CNS) infection-related mortality worldwide, with surviving patients often developing neurological deficiencies. While CNS inflammation has been implicated in the pathogenesis of CM, little is known about the relative...

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Detalles Bibliográficos
Autores principales: Xu, Jintao, Ganguly, Anutosh, Zhao, Jessica, Ivey, Michel, Lopez, Rafael, Osterholzer, John J., Cho, Clifford S., Olszewski, Michal A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406332/
https://www.ncbi.nlm.nih.gov/pubmed/34311579
http://dx.doi.org/10.1128/mBio.01076-21