The α2AR/Caveolin‐1/p38MAPK/NF‐κB axis explains dexmedetomidine protection against lung injury following intestinal ischaemia‐reperfusion

Intestinal ischaemia‐reperfusion (I/R) injury can result in acute lung injury due to ischaemia and hypoxia. Dexmedetomidine (Dex), a highly selective alpha2‐noradrenergic receptor (α2AR) agonist used in anaesthesia, is reported to regulate inflammation in organs. This study aimed to investigate the...

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Detalles Bibliográficos
Autores principales: Xu, Lin, Li, Taiyuan, Chen, Qiuhong, Liu, Zhen, Chen, Yuesheng, Hu, Kai, Zhang, Xuekang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406475/
https://www.ncbi.nlm.nih.gov/pubmed/34114328
http://dx.doi.org/10.1111/jcmm.16614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406475/
https://www.ncbi.nlm.nih.gov/pubmed/34114328
http://dx.doi.org/10.1111/jcmm.16614

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