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A Retinoid X Receptor Agonist Directed to the Large Intestine Ameliorates T-Cell-Mediated Colitis in Mice

Retinoid X receptor (RXR) is a nuclear receptor that heterodimerizes with several nuclear receptors, integrating ligand-mediated signals across the heterodimers. Synthetic RXR agonists have been developed to cure certain inflammatory diseases, including inflammatory bowel diseases (IBDs). However, p...

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Detalles Bibliográficos
Autores principales: Matsumoto, Ryohtaroh, Takahashi, Daisuke, Watanabe, Masaki, Nakatani, Shunsuke, Takamura, Yuta, Kurosaki, Yuji, Kakuta, Hiroki, Hase, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406631/
https://www.ncbi.nlm.nih.gov/pubmed/34475823
http://dx.doi.org/10.3389/fphar.2021.715752