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A Retinoid X Receptor Agonist Directed to the Large Intestine Ameliorates T-Cell-Mediated Colitis in Mice
Retinoid X receptor (RXR) is a nuclear receptor that heterodimerizes with several nuclear receptors, integrating ligand-mediated signals across the heterodimers. Synthetic RXR agonists have been developed to cure certain inflammatory diseases, including inflammatory bowel diseases (IBDs). However, p...
Autores principales: | Matsumoto, Ryohtaroh, Takahashi, Daisuke, Watanabe, Masaki, Nakatani, Shunsuke, Takamura, Yuta, Kurosaki, Yuji, Kakuta, Hiroki, Hase, Koji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406631/ https://www.ncbi.nlm.nih.gov/pubmed/34475823 http://dx.doi.org/10.3389/fphar.2021.715752 |
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